At the Urology Group of Princeton, we continually stay abreast of new developments, and potential treatments, in the field of Urology. For your information, we are sharing an interesting development on the forefront of kidney stone treatment.
Kidney stones generally leave the body without a doctor’s intervention; however, it can be a slow, painful process. MIT researchers have identified a potential new approach they hope will help patients pass kidney stones faster and with less pain.
In a lab dish, cells from human ureters (the tubes that connect the kidneys to the bladder) were exposed to 18 different drugs and, in so doing, it was found that two were most effective in relaxing the cells: nifedipine, currently used to treat high blood pressure, and a rho kinase inhibitor, used in the treatment of glaucoma.
In tests on pigs, injecting these two medications together nearly eliminated painful ureteral contractions. Subsequent tests found no traces of the drugs in the bloodstream; implying that this medication remains in the ureter, reducing the risk of systemic side effects.
The researchers hope to eventually test the treatment in humans to determine the optimal doses needed to help stones pass faster.
For tips on avoiding kidney stones, check out our blog post “Tips for the Prevention of Kidney Stones”.
If you have questions or concerns about your kidneys or kidney stone treatments, call the Urology Group of Princeton at 609.924.6487 or schedule an appointment online. The board certified physicians/surgeons at the Urology Group are experts trained to evaluate your symptoms, perform applicable tests, and develop the proper treatment plan.